Pioneering a Neuvae™ Forward in Healthcare

Measuring the Impact.

And we can go on and on….

The Statistics Are Not Lying.

AMR is in Desperate Need of a Solution.

The Problem With Antimicrobial Resistance.

  1. The problem with Bacteria is that it is very easily able to swap genes the way we swap baseball cards thanks to a process called gene transfer, either sweeping up antibiotic resistance in the genetic remains of dead bacteria or exchanging it during a sort of bacterial makeout session we call conjugation.
  2. Some bacteria like Staphylococcus have gained the ability to rebuild their cell wall faster than one antibiotic break it down. Other bacteria have “learned” how to make pumps that flush antibiotics out of the cell before they do their job.
  3. Antibiotics we DO have today have come mainly from the environment, we’ve adopted the natural weapons that microbes use to wage war on each other… but that also means they’ve had billions of years to develop resistance. It seems like wherever nature has developed an antibiotic, it’s also developed a way to fight it. Resistance seems like an inevitable result of evolution. Of course, we are doing our part to help the superbugs succeed.
  4. In some countries, people consume too many antimicrobials, often when they will not work. For example, it has been estimated that in long-term care facilities and general practices in the OECD area, up to 70% and 90% respectively of antibiotics are prescribed for inappropriate reasons. On the other hand, in other countries, people cannot afford to buy the drugs they need. In addition, antimicrobials are also heavily used in agriculture, often for no other reason than to make animals grow more quickly. Such ineffective use encourages AMR.

Introducing…Neuvae!

Our Solution.

  1. The First Pillar — Proprietary bacteriophage engineering process that can reduce the cost of engineering by 80% while allowing us to engineer custom phages.
  2. The Second Pillar — Administering the custom bacteriophage into the body and through its natural systems, target, disable and kill the resistant bacteria.
  3. The Final Pillar — Boost the innate immune response to the same bacterial infection by using immunomodulatory particles carrying antigens transported through the phage.

Why Bacteriophages?

Pillar 1: Revolutionizing Custom Phage Engineering.

All of this can ultimately revolutionize the process of discovering the most effective and viable mutation to increase the range of the phage.

The Phage Tail Fibers

Homologous Recombineering

BRED System

Phage Display

Pillar 2: Enhanced Bacteriophage Targeting and Bacterial Lysis.

Pillar 3: Immunomodulation through Transduction Particles.

Scaling Plan

Our scaling plan begins with targeting the two deadliest bacterial infections:

  • MDR tuberculosis
  • Pneumonia
  • Enterobacteriaceae
  • Salmonellae
  • Staphylococcus Aureus
  • Pseudomonas Aeruginosa

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16yo BCI Developer | Building Tools Necessary to Read + Write our Neural Code

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Mikael Haji

Mikael Haji

16yo BCI Developer | Building Tools Necessary to Read + Write our Neural Code

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